It is hard to read about Boethius without thinking of the devotions of John Kennedy Toole's protagonist Ignatius Jacques Reilly in "A Confederacy of Dunces", and his obsession with his pyloric valve.
“Well, what do you expect? The human body, when confined, produces certain odors which we tend to forget in this age of deodorants and other perversions”
It's the only place I've ever read about Boethius, and the first thing that came to mind. I wouldn't be surprised if more people have read A Confederacy of Dunces than anything written by Boethius, translated or not. Not to the detriment of Boethius; Toole's work is just that good.
There's also the medieval board game Rithomachia that is based on Boethian mathematical philosophy