Only if you value overseas travel... It currently takes ~16 hours to fly from SF to Singapore depending on weather. Any longer, and you're going to see a lot of that travel disappear.
It takes that long because it's more efficient to do it in a single flight. Taking off and landing are a massive waste of time and fuel. If we only had short range planes people would change their destinations in some cases or they'd plan layovers as part of the trip. I don't think you'd see that many people just stop travelling abroad.