Same with us. About 10% of our 700+ volumes are having problems right now.
It's hard to tell for sure since there isn't any load.
We're fine on EC2 -- but everything on RDS seems to be giving us big problems. We started a few backups before we new it was systemic, and all of them are stuck at 0%. We also tried spinning up new instances -- and they're all stuck in booting.
I think which physical data center "us-east-1a" etc. corresponds to differs from user to user, to load-balance given that people will probably be more likely to use 1a than the other zones.
We had about 45 min of downtime around 4am EST. Our RDS instances, EBS backed and normal instances all returned without problems. We are in Virginia us-east-1a and us-east-1b.