Yeah, just look at Gemini/Coinbase liquidity/volume vs. the offshore cowboy exchanges and it's clear that following regulations has a huge cost.
Also keep in mind that currently crypto is a lot bigger outside of the US, most of Asia don't want to deal touch things close to US regulators. Eg. it's why Tether is so much bigger than things like USDC (as they actively fight against US regulators in court to protect users).