I've probably had a dozen people with glasses use my headset. None of them seemed to have any issues with visual quality, though a couple had issues with comfort. The Quest comes with a spacer for glasses. That works fine 90% of the time, but some people's glasses are too big and can hit the lenses in the headset. This can be uncomfortable and (more importantly) it can scratch the lenses in the headset.

If you have glasses, I'd recommend getting some lens protectors for the headset. They're usually around $10 and take a minute to apply.

They work okay, but I recommend looking on Etsy and finding some magnetic lens adapters for about $25 dollars. They click into the headset and then you take the lenses out of of a specific $10 pair of Zenni Optical lenses and stay attached to the headset itself.

There are some companies that make custom lenses for the Quest. I've used one, and it works really well.

Of course, that's not for the model being shown here, I'm not sure if it's still an option.

I use a Quest with glasses and works good.

There is a special retainer that keeps the headest a bit farther away from your head.