I used to pop Rolaids for heartburn like crazy. I did this for years, until I was actually developing a toxic reaction to the Rolaids and I began trying other ways to control my heartburn.
I finally discovered that sugar (and alcohol) were my biggest contributors. So for me, sugar is definitely toxic. Now that I limit my sugar, I go weeks without heartburn, and when I do get it, it's usually because I had some beer or wine the previous day.
Based on this experience, I was interested that he talked about the fructose being removed by the liver (as alcohol is). I probably have some liver issue. This article has led me to a new avenue of research. In the meantime, I am a believer in limiting sugar intake.