Forget that hypster hype.
The problem is not the position but the length working in the same position. Whatever position.
If you stand the whole day, your legs will suffer (ask people working in shops); in the long run you will have "heavy legs" issue. You may lower the effects with a proper setup of your bed (feet should be 2-4 cm higher).
The only real solution: * A good physical activity: cardio + strengthening the muscle for "body protection". * Streching all the muscle groups.