If you're willing to go down a rabbit hole, designing your own keymaps and hacking on a layout can go a long way to alleviating RSI symptoms. The author doesn't touch on it but QMK will change the way you interact with a keyboard and make those tiny 40% and smaller boards feel a ton bigger.

When I made the layout for GergoPlex[2] I designed it around Vim/i3/Programming and other uses secondary. But because you can easily change it for your specific workflow weakpoints that you identify can be dealt with.

>Actuation force and travel probably matter more for RSI

I am not a doctor, but this matches my experience. I use 12g Low-Profile Kailh Chocs and noticed a good change in flare-ups as I kept driving it lower and switching to a non-MX switch.

I was able to get Kailh to manufacture lighter weighted Choc switches (gChoc, 20g Linear) for use on boards like GergoPlex and others. Reviews seem good across the board on those for people suffering from RSI, so I'll keep at it.

I'd argue that the main factors to be optimized for in decreasing order are: Split, Stagger, # of keys, layout, Spring weight, Travel distance. But getting there is a very, very strange time[1]

[1] https://blog.gboards.ca/2020/01/weird-keyboards-programmable...

[2] https://www.gboards.ca/product/gergoplex