Do you realize that there are thousands of scientific publications in medical image processing that address exactly the same concrete problem that you have?
It seems the primary way to detect regional wall motion abnormalities is with speckle tracking, which requires way too much post-processing for a clinician.
A system that segments the left ventricle and finds akinetic regions in realtime from a parasternal long axis view or an apical four chamber view would be pretty nifty.
If you know of a paper or system that does this now then please let me know. I would love for someone else to have solved this, haha.
My email is Davidm.Crockett [at] Utah.edu
Kudos for advancing the human race.