I've been out of the game development arena for a while, but I can't help but pause here. Are people really writing DAWs and big desktop app interfaces in Unity?
The last time I played with a game engine, I would have said UI was its weakest aspect. Clunky, slow controls, visually unappealing, and certainly lacking in accessibility. Without researching more, I would feel pretty confident placing a bet that if I pointed JAWS at a Unity Window, it would say "Game Window" and that's about it. Windows accessibility hooks and tab navigation certainly didn't work out of the box, and I would say that is bare minimum for a UI toolkit.
So while it's valid that Unity is a beast and game engines will eat the world for games, I have a really hard time taking them seriously for UI-driven application development.