Antibody tests show what parts of NYC were hit hardest
nytimes.com
nytimes.com
Edit: grammar.
"From corona (“crown-like circle of light appearing around the sun”) + virus.[1][2] Corona is derived from Latin corōna (“garland, wreath; crown”), from Ancient Greek κορώνη (korṓnē, “something curved; curved stern of a ship; end, point, tip”), from Proto-Indo-European *(s)ker- (“to bend, turn”). The name refers to the characteristic appearance of its virions by electron microscopy, which have a fringe of surface projections creating an image reminiscent of a solar corona.[3] Compare the former genus name Coronavirus."
[1] https://www1.nyc.gov/site/doh/covid/covid-19-data.page
[2] https://opendata.cityofnewyork.us/
[3] https://datasmart.ash.harvard.edu/news/article/new-york-city...
I wasn't the OP but that was my underlying motivation linking to the direct data repository. The good news is that NYC provides basic visualizations across zipcodes and boroughs, and one of the visualizations allows for a breakdown by "poverty" level.
> The accuracy of antibody testing varies widely. Moreover, most antibody tests were done for people seeking them out, which means that those who got tested are a self-selecting group and not a random sample.
> It also appears that New Yorkers in some neighborhoods with lower infection rates were more likely to seek antibody testing.
> In some wealthy and largely white ZIP codes in Manhattan, some 30 percent of people may have gotten an antibody test. But in Corona, for instance, where the positive rate was highest, less than a quarter of people got tested.
The reality is probably just that these people didn't have damn time or energy to go to a testing center for a blood draw, or were already concerned about spending so much time in public and didn't want to travel more than they needed to. Being working-class in NYC is hard nowadays due to the very long commutes (caused in turn by people fleeing excessively high rental prices).
The test for me was $165, and my insurance would not cover it.
My recovery was punctuated with almost daily calls from the local hospital i tested at asking me to come back for a follow-up antibody screen for research purposes.
This was $400. It was not covered by insurance so I skipped.
I was then contacted by my insurance company asking if I had completed the antibody test and told it was covered, so I passed the antibody test and went back to work. Three weeks later I wound up fighting $600 from a hospital collections agency for covid ab lab work.
My disease advice is this: If possible, avoid being a working class American.
23k deaths, thus a 1% mortality rate.
I guess this the final nail in the "this is just a flu" .
The immune system isn't just about antibodies. having antibodies, for this disease, means you were exposed relatively recently. People who had the disease months ago are now showing a lack of antibodies. That doesn't mean that their immune system isn't primed for this disease, just that they currently do not display antibodies in their bloodstream. Thus it is likely many more than 2.4million americans have been infected/exposed, potentially drawing down the death rate well below 1%.
The parent poster is not saying 2.4 million Americans were infected. The poster is saying 2.4 million New Yorkers were infected.
1% would be to high given the data elsewhere.
Did the population this study looks at have a death toll of 23k and what was the population exactly?
I'd think a top priority in the world would be to tie this number down properly. And this study seems solid.
The fact children are a higher infection rate in the study is not good, because it implies the mortality rate is higher again than 1%.
I still think we could have gotten through this quicker if we didn’t lock down the young and healthy, while taking extra care to keep at risk populations safe.
https://www.washingtonpost.com/health/2020/08/20/children-co...
So, probably the mortality rate is higher. I wonder if there is any bayesian tricks to estimate the infection range given 1/8 people got tested, regardless of selection bias.
edit: actually the overall deatheate could be lower, because we know the number of deaths, but not the exact number of infected -- if overall the infection rate is lower then 27%, the deathrate is lower than 1%.
We only know estimates of the number of deaths. The correct number lies somewhere between the official number of covid19 fatalities and the total number of deaths during the same period, because one hand you have excessive mortality and on the other hand you have changes to the baseline due to changes in behavioral patterns. Excessive mortality are higher than officially recognized covid19 deaths and serve as a more accurate proxy for real covid19 deaths, but at the same time the baseline mortality might vary as well.
That would be pretty interesting.
There's a lot of studies saying that antibodies go below detectable levels within 2-3 months, even though that doesn't seem to mean that these people are no longer immune.
It's also possible that some people are fighting off COVID via a T-Cell response while not developing significant immunoglobulins or that immunoglobulin levels fade quickly while T-Cells don't. Those people can also test negative for immunoglobulin antibodies despite fighting off the disease.
So it's actually more likely that these tests are significantly under counting exposed people in total. But these tests aren't perfect and for any specific person, they could give you a false positive or a false negative result.
A positive test result shows you may have antibodies from an infection with the virus that causes COVID-19. However, there is a chance a positive result means that you have antibodies from an infection with a virus from the same family of viruses (called coronaviruses), such as the one that causes the common cold.
https://www.cdc.gov/coronavirus/2019-ncov/testing/serology-o...
I have not read enough on this specific NYC testing to know for sure if they control for that somehow, or if controlling for it is even possible. Seems like it would be a factor, though.
Not always. Famously, cowpox antibodies protect against smallpox.
My read is that test subjects were entirely self-selected, which mean strong bias to those who suspected (or feared) exposure, had access to testing, and (where and when necessary) could pay for same (I don't know whether or when NYC instituted universal free test access).
That's in addition to any issues with test accuracy, procedures, or reporting itself.
The information tells a story. It's not immediately evident just how accurate that story is, an uncertainty which may further muddy conversations and decisionmaking regarding the outbreak.
As any statistician worth their salt will tell you, sample size is vastly less relevant than sample method, and a rigorous, though small (a few hundred, perhaps 1,000 or so randomly selected casess) would be highly valuable. The alternative (at far greater cost) is near-total testing. Itally have conducted comprehensive testing within specific small towns. Some smaller countries and territories (Andorra, Faroe Islands, Monaco, Luxembourg) have attained 100% test coverage. These still suggest 1-6.% CFR.
New York City's test coverage, whilst large, could still remain quite biased.
Really it comes down to 3 dimensions:
1. Where do we direct tests
2. Where do we allocate non-pharmaceutical interventions
3. When ready, where do we direct a vaccine
These are all questions that we can find a signal for within the data. There are obvious constraints, such as reagent and pharmaceutical availability and the viability of certain policies.
I’m flabbergasted and agitated that on the federal level we haven’t come to a consensus on testing and data. If there is anything certain to increase harm relative to where it could be, it’s this “slow down testing” narrative.
This is just speculation, obviously
It's not - Corona Park and Elmhurst were the two hardest-hit neighborhoods from near the very beginning.
https://en.wikipedia.org/wiki/Irony#Cosmic_irony_(irony_of_f...
He says a few seconds into your timestamp. Thank you for trying to soothe my thoughts. But now I'm even more concerned. Wouldn't that render a vaccine pretty useless if it's gone after 4 months?
Still, it's an absolutely brutal way to handle the virus and it's accepting deaths on the order of large wars.
If you're thinking of the vaccine as a tool to ensure people can't get infected at all, then yeah, it won't be useful for that purpose. The goal isn't to eradicate the virus, just to get it under control so it's not such a huge public health concern.