Conventional wisdom says it's impossible to run in AGB Compatibility Mode and retain DS functionality, but I still wonder if it could be done.
Also given the ancient cryptography, I wonder if it's possible to crack DS Download Play and introduce a new "Wireless Multiboot" exploit that uses real DS hardware similar to the early exploratory attempts using "NDS WifiMe" before flashcards become commonplace. The hardware only has ~256 kilobytes of RAM (and doesn't even use a standard Wi-Fi stack if I recall correctly), but it would be SUPER COOL from the perspective of getting hardware to do something never thought possible.
One use-case for this hack I imagine is playing Zelda Four Swords Adventure played on a Wii / Wii U (via "Nintendont"), with the game patched to use Wi-Fi for the communication to the Gameboy Advance controllers rather than a Link Cable. The players won't need to have a flash card each, but could boot up the payload using DS Download Play on any DS variant (including DSi and 3DS).