I remember someone got linux running on one of them and ever since then I wish that that form-factor for small computing had taken off.
Imagine if the raspberry pi people made devices like this.
I know how you feel, but the form factor I prefer is PCMCIA[1].
Interestingly, someone did, in fact, attempt to create a small, modular, computing standard based on PCMCIA - the card was a compute module that could be inserted into a shell laptop ... I cannot find the link, unfortunately ...
[1] "People Can't Memorize Computer Industry Acronyms"
On a slightly different take, Octavo makes Pi Zero like devices (single core, 512MB) but with Ethernet and (IIRC) eMMC memory within a single package itself smaller than an SD card. I would love to design a board with a couple of them and a network switch.
So, the host computer would simply address the WiFi chip on the bus, and issue commands and transfers, similar in overall design to how it would talk to a PCIe device or USB device.