Thus, the metagame includes knowing when to guess (since, for time-beating purposes, it is optimal to instantly guess as soon as you identify that a guess is necessary, not just to speed up that particular playthrough, but more importantly because it will allow more playthroughs to be performed in less time).
Similarly, part of the metagame includes figuring out how best to make initial guesses. Is it better to always initially make 1 guess, or 2, or 3, or does it depend on how much of the board the first guess opens up? Etc.