Nuking your starter base is silly unless you're on death world and have some impenetrable defense set up that's hard to attain elsewhere without significant work. Usually to start a fresh megabase you just load up a car and drive a couple minutes to a new location. Then you can keep supplying the construction materials of the megabase with your starter base. (To those unfamiliar: yes, "the end of the game" -- launching a rocket -- is really the start of the game to seasoned players, so the initial base you launch the first rockets with is commonly called the starter base.)