Absolutely. This actually a type of relationship that many businesses have. Most hair salons don't actually employ any hairdresser. They employ the people that clean the shop, and run the register. But the hairdresser themselves are independent and lease a stall in the shop. The salon very much depends on the independent hairdressers to function.
Pointing out that Uber would cease to function without independent contractors is entirely correct, but does nothing to demonstrate that that these workers should be categorized as employees rather than contractors.