Whoa, that's a well designed ISA.
BTW if unaligned 32 bit instructions are a concern there is a Compressed NOP (C.NOP == addi x0, x0, 0 but without RAW hazards).
It's simply Not That Hard to deal with. You just need to have two 32 bit words in your instruction decode buffer. Sometimes you need the 1st half of the 2nd word and sometimes you don't.
Incidentally, once you've done that, arbitrarily aligned (on halfwords) 48 bit instructions don't need anything extra.
Additionally, I believe experimenting with vector ISAs was mentioned as one of the reasons they started another RISC research project, which ended up being RISC-V.
https://people.eecs.berkeley.edu/~krste/papers/EECS-2016-1.p...