Facebook c. 2010 was too confusing for me, so I bounced off (from descriptions of what it was like a couple years before that, I think I'd have enjoyed it then).
Twitter's been too confusing for me to understand for years, I can barely follow what's going on when reading it, let alone use it (I've tried within the last couple years, and never got the hang of it). Used to be easy for me to read & use but the interface and interaction options don't make sense to me anymore.
I didn't even figure out that Instagram was supposed to primarily be a social site/service, despite repeatedly being exposed to it, until some time after the Facebook acquisition.