Yes, in 1Password's 2FA announcement its head of security mentions that using 2FA in 1PW does not give you true 2FA:
> If you would like to turn a site’s offering of TOTP into true two-factor security, you should not store your TOTP secret in 1Password (or in anything that will synchronize across systems).
They mention multiple times that if you want true 2FA the second factor needs to be on a different device or a physical key like a YubiKey.
Then they say that “two-step” security offered by 1PW + 2FA is probably enough for most use cases, and that 2FA in 1PW still has additional value because (a) some sites require 2FA and (b) one-time passwords offer protection against sniffing passwords over insecure networks.
https://blog.1password.com/totp-for-1password-users/
The fact that 1PW even auto-copies the code to your clipboard after auto-filling a password so that you can paste it in when prompted raised my eyebrows when I first used the feature, though. It's very convenient but it's obvious at that point that you're throwing away the protection that storing the key on a second device would offer, even if 1PW requires you to authenticate before the app will open.