I mean if you are going to potentially die otherwise then that's one thing. But if you go to the doctor with a sore throat and they hand you some random script for something you've never heard of, hard pass is a pretty good strategy.

The appropriate way to make medical decisions is based on data, but if a drug is still under patent then the data isn't there.

You are right, 50 years is probably smarter, 20 is too little for all the effects to come out.