Of course, designing with accessibility in mind is important, but I would argue supporting Links isn't.
I use firefox as my daily driver, but I still test in chrome and links.
How unpleasant. Have you found that the W10 VM takes way more disk space then seems reasonable? I had to fire one up the other day, and between the VM image and the VM it took 50ish gigs of space iirc.
It'd be interesting to do a market research study on what the impaired population for a given vertical is, and put some data-driven arguments behind adding support for accessibility.
Honestly, doing that would probably improve the UX for people with normal eyesight as well, because it'd force you to think about document layout and component interaction carefully.