Highly creative people generally rank low on conscientiousness. Organisations as they grow need ALL their employees to be conscientious: organised, punctual, goal-oriented, accountable - to not just to control outcomes but maintain cohesiveness.
Organisation culture stifles those type of people.
For an organisation to keep their innovators they need to be siloed away in an autonomous 'Skunk Works' where they can be free from the bureaucracy required to run a company.