It really depends how you structure your code. While my Qt apps are very much coded against Qt, it’s actually pretty easy for me to currently switch them to other UI frameworks as needed. I’ve done this with some of my bigger tools going to other frameworks.

If you keep your logic separate from your UI, and interact via method calls, it’s not very hard to swap out the underlying object. Arguably, it’s the pattern Qt encourages anyway so that you can flexibly change your UI design in the future