Opium -> Heroin -> fentanyl
So maybe legalize opium?
The other thing is there is a huge difference between by a powder that you don’t know what’s in there versus buying a 100 ug ampoule of pharmaceutical fentanyl.
People tend to trust that their doctor is right. If the doctor gives you oxycodone, you assume that it's safe.
Tied in with that is the increased availability of heroin and fentanyl, and now decreased availability of prescription painkillers, pushing users from taking relatively safe pills to injecting drugs, which is an order of magnitude more damaging.
Scary.
My wife for one, even 5mg Vicodin would give her unbearable nausea and head spins.
Whereas that plus a glass or two of wine would be very (too) enjoyable for me.
Not everyone said weed wasn't dangerous either. Leading up to cannabis deregulation there were any number of experts warning of disaster due to its claimed severe effects.
The point of the deregulatory argument is that you can't really entrust a homogeneous monopoly to act optimally, because there's lack of competing perspectives and alternatives.
The current drug regulation regime has failed in all sorts of ways that go far beyond drugs of abuse, into siphoning off funds surrounding less recreational substances, through rent seeking. Anyone who has tried to get a prescription for something harmless or nearly so that they've taken for years can attest to this. Acyclovir, for example, is an essential medicine per WHO, and articles have been written in which it is acknowledged to be safe for the general public (with empirical data) but still argued should be kept as a prescription to avoid viral resistance (even though there's no evidence of this, and other sources of microbial resistance are routinely ignored).
The current system has failed in part because discussions are presented in this black and white fashion where it's things stay as they are or nothing. Pharmacists could be used much more than they are, for example, as could other provider types, not just for drugs but for lots of things.
The pandemic is full of other examples. The CDC demonstrated early on how regulation can fail, and people managed to poison themselves without involving prescribers or their illegal drug dealing counterparts at all.
That's what I'm really unsure about, the physical and psychological addiction potential and an extreme stance which would take it as justification, that the victims are weak of will. The eugenics argument would even encourage this as a way to selection for fitness. IMHO, the physical addiction is countered by the adverse effects of the come-down. I hold some arguments against it, but consider the psychological component much more important. 30% of first time heroin users became addicted in the last German federal report on domestic drug use. I'd say only 30%, in contrast to the myth of the immediate addiction--which is real in a sense, for if addiction-affinity is considered, it's effectively correct. Arguably, understanding the history, these people must be extremely racist, fascist, socialist, liberal, you name it, basicly selfish egoists in any sense you might find offensive.
Simple adversary population dynamics settle at an optimum in the infinite limit (I've watched a video by numberphile or so on the Logistic Function, haha). If the government is a regulator, it should seek to estimate the optimum. The pretense that the optimum is the extinction of drug use and users is ...
I have no idea what I'm talking about, lol
The opiate crisis happened because weed wasn't legal soon enough. Most opiate users for pain release could swap.
I'm sorry but I have to call you out on this. It's complete BS - we simply don't have anything that's remotely comparable to opiates for pain relief.
That being said I'll second that the opiate epidemic in the US is largely the fault of prohibition. Illegality feeds all sorts of negative cycles that wouldn't otherwise exist.
I wasn't saying they were comparable drugs. I was saying one is overprescribed for pain level that could be managed by something less drastic.
These people would be better off on thc.
Marijuana is a great replacement for those who never started down this path and okay a means of getting off opiates. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6777788/
The linked paper doesn't appear to me to make the claim you did. The combination group (the one from which you could validate the claim you made) is very small - only 486. In fact the paper appears to very carefully outline its own considerable limitations. The authors detail the lack of research in the area and point out a number of conflicting results, including results that directly contradict their own.
That being said, it is a well written, interesting, and thoughtful piece of research. It (and the nearby comment by waheoo) raise quite a few interesting questions for me regarding patient perception and how withdrawal symptoms might interact with marijuana. I also wonder which specific symptoms and underlying conditions might correlate with the various groups. I'm glad you brought this paper to my attention!