12c/24t, 64G with a high end video card.
tldr: upgrade GPU, downgrade CPU and ram to keep similar pricing.
The mobo cut is also a pretty useful savings, though it will be an obstacle to multiple-GPU setups.
Also, the parent comment misleadingly suggests that a 3900X costs less than $300. That seems like an error in pcpartpicker, since clicking through reveals a true price of $400+.
That bad boy costs $0.96/hr on the current spot prices (https://aws.amazon.com/ec2/spot/pricing/)
There are certainly some workloads where it makes sense to own your own storage and rent computation, but you can't assume that by default for a "powerful AI" workload.
The closest in performance to that GPU would be the V100 found in P3-instances.
https://lambdalabs.com/service/gpu-cloud
I'm embarrassed that I feel so compelled to post this--on a Friday night at that--I apologize.
Don't be. Finding gems like this is why some of us read the comments.
The closest you can get on AWS (more like System #3 in the paper with 4x GPUs) would be something like a p3.8xlarge instance [1] that'll cost you $12.24 (on demand) or $3.65 to $5 (spot price, region dependent) [2].
A single GPU instance (p3.2xlarge) only 16 vCores, though) will cost you $3.06 on-demand or $0.90 to $1.20 (spot).
[1] https://aws.amazon.com/ec2/instance-types/p3/ [2] https://www.aws4less.com/AWS/AWSCurrentSpotPrice.php