In my org we struggle with this because of two combating philosophies -- the first one is the obvious one, "Keep it short and sweet so it's easy to understand and review."
The other side is, "Please stop creating PRs and checking in dead code that is never executed until a promised future PR unlocks it."
My particular product is very complex (read: messy) and minor changes involve lots of work to maintain back-compat.
When we tried the "small PRs", we gained easier reviews... but ended up with so many changes that require a future PR to complete the work, and the future PR never comes for some reason or another. Another problem for reviewers is "Even with the PR description filled out, I don't see the value of this PR unless I see all of it together."
If you're reading that you probably scoff, "Just fix your process" or "Tackle your technical debt so your PRs are simpler!" You're not wrong, but if only it were something that could be done in a week and not years :)