The article mentions that Python malware comes with difficulties but in my experience it has the advantage to be an easy and simple way to write reliable malware. Packaging with PyInstaller to create a single (but large) executable is easy and helps avoiding detection as the interpreter is embedded in the PE (I never went in depth on this topic but it would be interesting to check out).

Shameless plug; I wrote a few popular articles on 0x00sec about Python malware on Windows just to show how simple and easy it is to build either using ctypes to call WinAPI functions or using pywin32 wrapper which makes the whole thing a lot faster.

See part 1 here https://0x00sec.org/t/malware-writing-python-malware-part-1/...

Definitely not the way to go if you have limited memory and need to write tiny shell code but it’s good enough for a stage 2 payload.