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Any time you want to leave that vendor. If they up their prices greatly, reduce service levels, refuse to give attention to improving service levels.. break a clause in the contract... an so on.

While this is true in theory, I don't recall a single instance of AWS increasing pricing or reducing service levels - not saying that is impossible, but it hasn't happened so far (at least that I remember)

When you deal with google cloud and they up their price. Didn't see it with the other vendors though.

It's simple, you are not stuck with a vendor.

A practical example that happened to my employer recently : we migrated to Microsoft Azure when they opened two datacenters in our country. We didn't have to change any code because we don't use vendor locked solutions.