I've found an easy way to bypass this issue though: Click Share > Embed, the preview window is playable. Start playing video from there, put it on full screen, profit!!!
Couple weeks ago using ublock origin when browsing youtube would make youtube almost unusable. For me - if I'd have a direct link to video - the video would load and show, but the website itself wouldn't. Basically from user's point of view it was completely blank page with only video showing, no related videos, no comments, no like/dislike or anything. :)
So I needed to turn off ublock origin for youtube and everything came back to normal. I am using pihole though, but it was basically useless for youtube ads.
Though couple days ago, I've turned on ublock origin and youtube was working as usual and it was ad-less.