It's certainly something to think about when so much today revolves around giving the government even more power and control, all the way down to what we can say.
The Cherokees made up a large portion of the "Trail of Tears". The saddest part is they were largely fully "assimilated" into the "American" culture at the time. Most were fully "Christianized", spoke English, they translated many church hymns into their native language, built towns, and lived in houses. All like the "white man". Then they were asked to give up their guns and property and start marching.