In the books, there is an electronic guide to the combined knowledge and wisdom of all the various species that inhabit the universe. The guide is itself called "the hitchhiker's guide to the galaxy."
I have always interpreted such titles to be a reference to this in-universe guide rather then to the novel or its characters.
We could split hairs over the fact the in-universe guide is more analogous to Wikipedia in scope and scale than a more condensed tutorial or primer, or whether the reference is obscure enough that it confuses, alienates, or distracts readers who aren't part of the intersection of Hackernews Readers and Hitchikers Guide fans.
It never really bothered me but I was a huge fan of the series when I was younger.
Edit to add: as I am a technical writer on the side, it's a timely reminder to avoid any analogies or cultural references that require knowledge others in my target audience might not share. So, interesting point!