Yeah - I think Zuckerburg said that "it's better to make lots of quick mistakes" because you learn more quickly and that culture of fast, small changes to your product will generate a better result, in the end. It reminds me of the saying: "the bridges I burn light my way!"
A friend once told me that an MBA teaches you all you need to run a business theoretically, but only making decisions whose outcome you are not sure of gives you the experience you need.