I've evolved a Perl/Tk app (forked from
http://cscrape.sourceforge.net/, but there's practically nothing left of the original cscrape code except GUI bits) that sniffs Craigslist RSS feeds and applies additional filters (beyond the limited search capability offered by CL) before presenting the results. Compared to reading CL RSS feeds in Google Reader, I'm definitely suffering less information overload. Maybe there are other RSS readers that offer such custom filtering, but this way I can add whatever feature I need (with full access to Perl facilities), when I need it. Also, though I cannot prove it, I suspect that basing this tool on standard RSS feeds is less burdensome to CL's servers than scraping the site ad by ad.
P.S. The XML in CL feeds makes the Perl XML parsers I've tried barf, so I had to write my own. Again I'm speculating but I suspect that (replacing the XML parser) would have been challenging to do in a "RSS Reader".
Edit: less pejorative comment on CL's intrinsic search capabilities.