She's not arguing for stopping scientific research, but finding more optimal ways to do said research. She has continuously been pointing out that the particle physics community behaves like a cabal. There is little if any progress or evidence of future progress yet they keep increasing costs and forging ahead with their -surely by now flawed- interpretation of scientific research.
Sabine Hossenfelder outlined a lot of unexplored scientific areas that are ripe for research and proposed a lot of alternatives.
The main issue is clearly the sunk cost fallacy. At some point, scientists need to cut their losses short and re-align themselves with more promising avenues. The reproducibility crisis and string theory debacle proves that scientists are not immune to biases, short-termism and self-serving behavior.