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I use Safari for personal surfing, and separate Chrome accounts for my various business/work related surfing.

Keeps things separate and tidy, and I keep Chrome closed as much as I need it to be closed.

I like this idea a lot. I've been using Station to stay logged in to all my various work web apps, and then Chrome (now Safari) for personal.

I use Mailplane for when I want to see all my email accounts, and Spark when I want to deal with all email accounts together.

Each work Chrome profile has a pinned Gmail and, maybe, a Slack.

So I can be universal, or targeted, where I want to spend my time.

That said, I'm also spread across too many endeavors, but that's a totally different problem.