IronPython 2.7 released with VS integration, full Python 2.7 support
ironpython.codeplex.com
ironpython.codeplex.com
I've been using IronPython at my day job, an all-MS hospital, to write scripts and utilities that integrate with the rest of the ecosystem and supports the work of the main medical applications(.Net based). Using Python for scripting allows me to iterate quickly and saves a lot of boilerplate code.
I use a bunch of IronPython scripts for stuff like pre-generating cache records from our dead-slow database and determining usage patterns. I also use MongoDB for offline processing but i use cPython for that.
One thing that annoys me though is the startup time and I really hope that someone is working on this. The articles mentions a small decrease and so hopefully that's just a step forward in the right direction.