As someone who has used Angular 2 since beta, I can tell you, it's been a bumpy ride nonetheless.
> its target audience - large companies making large-scale applications - is fairly conservative
React was built for Facebook, which is a large company building a large-scale application.
> All this won't matter once the next gen compiler-frameworks reach maturity.
And here I am using HTML and CSS with tiny sprinkles of JS for most websites, and it's working just fine, and has been for many years.
Personally, I hope that server-side rendering will be the new ~old~ trend.