You lose facilities like: goto source, search/replace, modifications (I might modify/format a piece of code temporarily, to help me understand it better, might rename functions, variables, add lines to visually separate parts of code, etc) and many more.
You re-enforce your discomfort with reading/writing code on the screen. I'm trying to assume different reasons that you might have to learn a code and for all of them that I can imagine, you'll be better off as someone who feels at home with the screen. So I suggest you to resist this temptation and do what you ultimately will do.
Out of curiosity, Is your job/situation/skills in a way that being good with screen will not seriously benefit you? How?