That is my current strategy, i.e., to work with the yaysayers. "Why me" would be the least of my worries. My biggest hurdle was getting a Ph.D degree in a highly multidisciplinary field and that's now out of the way.
If you have already cleared the biggest hurdle you can think of, why the grudge? It should be smooth sailing for you from hereon out.
I was mainly talking about my friends (most, actually all, of whom are naysayers) and people I interact with online.