I don't necessarily think that these kinds of non-lethal weapons can't be used in a "safe" or situationally appropriate way. The problem is that all of these non-lethal weapons have safety guidelines that need to be followed or else they're actually quite dangerous and have high rates of injury (even severe injury). As US law enforcement has shown repeatedly over recent weeks, they're not following any of these guidelines. People are being blinded because they're shooting rubber bullets at people's heads (against guidelines). They can't be trusted with these tools.
I don't think it's solely a US problem either. French police is incredibly eager to liberally apply pepper spray to defenseless protesters (who've committed the heinous crime of exercising their right to free speech and their right to assemble). People are also injured whenever German police use water cannons.