To do "template drop out", it would seem productive to look longitudinally across pages on a single site, or in a subdirectory. For instance, almost all pages in Hacker News have the same chrome. Methods used for DNA clustering (such as Hidden Markov Models) could quickly find 'conserved' and 'unconserved' areas of documents.
This touches semantic technology because it links the ability to find nameless statistical patterns with meaningful semantic identifiers, such as domain names.