The Firefox version has the ability to block third party scripts masked as first party ones through the use of CNAMEs. Chrome doesn't expose APIs to let extensions do it.
> The blocking ability of the webRequest API is still deprecated, and Google Chrome's limited matching algorithm will be the only one possible, and with limits dictated by Google employees.
Firefox + uBO + uMatrix will block everything you can reasonably block without making your internet life miserable in the other extreme (although uMatrix can be a pain sometimes).
If I could force every webdev to browse their site with a fresh uMatrix install I would.
https://github.com/gorhill/uMatrix/wiki/How-to-create-rules-...