If we are to learn anything from the last 10 years of the replication crisis, it has to be that a single paper is a data point, not a conclusion.
There is a whole field of science dedicated to the statistical analysis of multiple studies in prior literature, e.g. just search for _Meta-analysis_ in the context of medical research.
A state-of-the-art Meta-Analysis is indeed the strongest level of scientific evidence you can have to advise a healthcare decisions or guidelines.
The only purpose of these journals with what they call a high 'impact factor', is that they typically have their peer reviews performed by people who are regarded as the _best_ in the their particular field. Nevertheless, to assume that an expert cannot be conned is also naive.
edit: typo
I highly recommend this elaboration upon that idea: https://slatestarcodex.com/2014/12/12/beware-the-man-of-one-...