Can you start playing audio, go to System Preferences -> Date and Time -> Unlock the panel -> repeatedly uncheck and re-check "Set date and time automatically" and see if that causes audio glitches? There's a known problem with that series of MBPs, I believe with the T2 chip. I'm still on the 2015 Macbook so I can't test it, but another audio pro I know says some recent Catalina update fixed it, and before that they did their live shows with it unchecked and didn't have a problem.