Found problems with USB devices on day 1 with USB 2.0 devices intermittently freezing.
Documented https://www.reddit.com/r/mac/comments/gp5b1z/usb_20_issues_o... , and there is a workaround... do not use any hub that shows a USB 2.0 device to the Mac, find and use a USB-C hub that presents everything as USB 3.0 to the Mac even if it's USB 2.0
I believe that this is a Catalina software bug, and now I have a workaround I am happy. Sucks for those who can't figure out the debugging though.