My scripts end up longer and more verbose typically (I might just not be great at Python) but also a lot more maintainable (I am not great at writing maintainable Perl and I use Python more often).
I also use Node.js for this a lot because of the ecosystem containing so many accessible scripts and dependency management while not great is heaps better than most other ecosystems.
Of course OpenBSD can't do that with Python rather then Perl (as explained in that email). They have a different set of constraints. I am only saying in practice I have found Python to be the better alternative for my personal stuff.