I do keep track of if I already unsubscribed from a related list. Sometimes "unsubscribe from all" is completely ignored. Which really angers me.
If it's a random, clearly bought newsletter list from a related list, it depends on my mood. Likely spam.
Other notorious example: business A founder also founds (unrelated) business B. They just email their entire A client base with zero association to A. Big peeve of mine.
-- Edits (some more ramblings) --
My personal favorite: the "I want to receive marketing email" checkbox that rechecks if you have an unrelated issue with your transaction. Say, invalid CC details.
Still, even with these boxes, I think my standard is just: "I did business with them, I will get at least 1 marketing email. I'm ok with that. I will unsubscribe and not hear from them again." Anything past that is unacceptable.
To be clear: that's not how I think it should be. It's just how businesses, even small, genuine mom and pop shops, have been taught to operate. It's cultural. It reminds me a lot of tipping in the US. I'm vehemently anti-tipping "culture" because a standard 20% is the opposite of rewarding for performance. But I still tip at a baseline of 18%+.
It's too ingrained. And I'm not going to protest by not tipping and try to change it.
I think we've come too far unless changed by law or restaurant management. Same goes for marketing emails.