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Telegram's desktop client uses Qt and all widgets are custom.

Quite easy, unless one saves money on designers.

I use the free wxFormBuilder designer, which works great.

I meant people that work as UI/UX designers.

Average Qt (widgets) apps look much nicer than most modern whitespace-vomit webapp monstrosities

I agree. I just meant that the look of Qt and wx widgets is essentially equivalent (and not a big deal after all).