My family is Scottish, though I've been in the US since I started primary school. Several of my dad's school friends split time between the UK and various European locations with better weather (south of Spain, etc). That sounds pretty much perfect to me.

But, within the US? I'd be tempted to buy a plot of land in the Appalachians, maybe outside Roanoke VA, build a little chalet, and just chill out. Money no object, I can fly to NYC or London when I get the itch to do culture.

Edit - in DC metro now. It has a lot going for it, but some massive flaws too. I'm an hour from the mountains, which I love. 3-5 hours from several beaches - I could live without them, but it's nice to have the option. The city itself is pretty good for culture and dining. True four seasons, to keep it fresh. But, August is miserably humid. And while not that far north, by the time February rolls around, I'm ready for long summer evenings. Traffic is terrible. But, I walk to work.