As a Rochester native and current resident, this is really great. If you're ever in the Finger Lakes region, the Strong Museum is absolutely worth visiting whether you have kids or not for the Toy and Video Game Halls of Fame.
I have very fond memories of Rochester. Absolutely beautiful part of the world.
At various times, they've displayed a Sesame Street play environment, a Wegmans supermarket play environment, some Kinect-like projection stuff when that was in vogue, some arcade cabinets with pivotal games, and a greenhouse with live butterflies. They also have some collections on display in a quiet environment, such as a large collection of creepy, disintegrating American dolls through the ages.
The Strong is an important center of scholarship and has any number of culturally important artifacts in its collection, but who really has fun visiting it, other than play groups of young children visiting the pretend supermarket?
Those are all part of their permanent exhibits.